Description

Position Summary:

Our group studies both genomic and non-genomic actions of thyroid hormones. Current projects map
membrane-initiated receptor/signaling networks—spanning cytokines, growth factors, and GPCR
pathways—that drive genomic, structural, and functional adaptations in the heart and vasculature. We
place special emphasis on β-adrenergic desensitization, septic cardiomyopathy, and vasoplegia, with the
long-term goal of informing the development of new therapeutics to improve survival in sepsis.

Approaches & Resources

You will join a collaborative team leveraging: - Molecular biology: cloning, vector design, EMSA, protein–
protein/DNA–protein interaction assays. - Cell & tissue platforms: primary cells, iPSC-derived
cardiomyocytes, tissue models. - Imaging & physiology: live-cell biosensors, super-resolution microscopy,
patch-clamp electrophysiology. - Omics: targeted proteomics and transcriptomics. - In vivo models: small
and large-animal models of septic shock and myocardial dysfunction.

Requirements

Key Responsibilities:
- Design and execute experiments; analyze and interpret data with rigor and reproducibility. - Drive
manuscripts, figures, and conference abstracts/presentations. - Collaborate across cardiology, critical
care, and biostatistics teams; mentor junior trainees as appropriate. - Contribute to protocol/IRB/IACUC
documents and lab SOPs.
Minimum Qualifications
- PhD (or equivalent) in Molecular & Cell Biology, Biochemistry, Biomedical Sciences, or a related field. -
Hands-on expertise in core molecular and cell biology( e.g., cloning/construct design, PCR/qPCR, EMSA or
related DNA-binding assays, immunoblot/Co-IP, primary cell culture).
- Strong quantitative skills, clear scientific writing, and a record of productivity (publications or preprints).
Preferred Qualifications
- Experience with GPCR/β-adrenergic or thyroid hormone signaling. - Proficiency in protein–protein
interaction assays, reporter systems, or chromatin methods. - Advanced live-cell imaging. - Familiarity
with animal models of cardiovascular disease or sepsis; AALAS/IACUC training.
Training Environment & Support
UC Davis offers an outstanding, interdisciplinary environment with access to state-of-the-art cores
(genomics, imaging, proteomics) and close ties to critical care and cardiology programs. The position
provides strong mentorship toward career independence and grant writing.
Appointment Details
- Start date: Flexible (review of applications begins immediately and continues until filled). - Term: 1-year
initial appointment, renewable based on performance and funding. - Compensation: Commensurate with
experience and aligned with UC/NIH guidelines; full UC benefits.
How to Apply
Email a single PDF to Joaquin Lado, MD, PhD at jladoabeal@health.ucdavis.edu with: 1) Cover letter
describing your research interests and fit, 2) CV, and 3) Names/contact information for three references.
Format guide:
Job Title: The title should include the appropriate classification.
Reports To: This would be the working title of the career staff this position reports to.
Department Summary: Please provide a short summary of the department that is hiring for this position.
This will ensure that Postdocs have an understanding of the department that they may potentially work
for.
Position Summary: This is a brief description/overview of the position.
Key Responsibilities: Detailed list of at least 4-6 specific Essential Job Functions that are associated with
this position. Please be as specific as possible in your description to ensure your position is properly
classified. Ask yourself, what are the duties and responsibilities that are critical for this position to
perform?
Minimum Qualifications: What are the skills, knowledge, abilities, and experience required for the
Essential Job Functions?
Optional - Preferred Qualifications, if any: What are the skills, knowledge, abilities, and experience that
are not required, but will benefit the student to complete the Essential Job Functions?
As a condition of employment, the applicant will be required to disclose if they are subject to any final
administrative or judicial decisions within the last seven years determining that they committed any
misconduct, are currently being investigated for misconduct, left a position during an investigation for
alleged misconduct, or have filed an appeal with a previous employer.
Additional language will be incorporated into the job description:
“Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous
place of employment, including, but not limited to, violations of policies or laws prohibiting sexual
harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical
conduct, as defined by the employer.
o UC Sexual Violence and Sexual Harassment Policy
o UC Anti-Discrimination Policy for Employees, Students and Third Parties
o APM - 035: Affirmative Action and Nondiscrimination in Employment
To implement this process, UC Davis requires all applicants for any academic position to complete, sign,
and submit an "Authorization to Release Information" to your hiring department as part of the
application process. If an applicant does not include the signed authorization with the application
materials, the application will be considered incomplete, and as with any incomplete application, will not
receive further consideration.