Company Profile
Monell Chemical Senses Center
Company Overview
At Monell, world-class scientists are unlocking some of the most fundamental mysteries of what makes us human. How do we use our chemical senses to communicate? What are the cellular underpinnings of taste and smell that contribute to the difference between lifelong health and chronic disease? How do our chemical senses shape human nutrition? Which genes are responsible?
Monell’s long-standing interdisciplinary model was itself a scientific experiment when the Center was founded more than 45 years ago. Today, Monell remains a nexus where outstanding scientists from many disciplines work together to focus on a common objective: understanding the mechanisms and functions of taste and smell and how these senses relate to human health. The Center’s integrated research approaches range from basic molecular biology to behavioral neuroscience, from cellular biology to comparative ecology, from analytical chemistry to clinical work with human patients.
Monell scientists are at the forefront of discovery, exploring the senses of taste and smell in order to answer pressing questions about health, behavior, and the environment that we could not even foresee a decade ago.
Company History
In the 1960s, very little was understood about the essential mechanisms and functions of what were thought to be the “minor senses” — taste and smell. As a junior professor in the veterinary school at Cornell, Dr. Morley Kare became increasingly interested in this field as he investigated food choice in a variety of species. With encouragement from the government (e.g., the National Science Foundation and the Veterans Affairs Administration) and from several corporate leaders, Dr. Kare envisioned a multi-disciplinary scientific institute dedicated to the study of these senses that are so central to human health and well being.
THE BEGINNING
In 1967, The Ambrose Monell Foundation made an initial pledge of $1 million to create the Monell Chemical Senses Center, with Dr. Kare as director. After consulting with several universities, Dr. Kare, the directors of the Monell Foundation, and administrators at the University of Pennsylvania agreed that Penn would be the ideal location for such a research institute.
When the Center opened in 1968, its organization was unusual for the times; it began as a joint venture involving academic, government, and industry scientists, when such collaborations were rare.
The Center was first housed in the old Lippincott Publications bindery building owned by Penn at 25th and Locust Streets. In 1971, Monell moved into its current home at 3500 Market Street, initially occupying just two of the building’s six floors.
Early in Monell’s history, Dr. Kare said, “Monell itself is a scientific experiment.” The results of this experiment have surpassed hopes and expectations. From a fledgling organization, Monell has grown to be a major force in scientific research, addressing issues such as human flavor and fragrance perception, nutrition and diet, obesity and metabolic disease, population regulation, homeland security, environmental chemical exposure, and pollution effects.
Monell’s growth was rapid, and in 1978 the Monell Center separated from Penn to become an independent nonprofit research institute. The two institutions continue to maintain a close relationship.
FULFILLING THE MISSION
The Center, now with approximately 40 PhD-level scientists, fully occupies the 60,000 sq ft 3500 Market building as well as almost 30,000 sq ft of space in 3508 Market St, which was purchased in 2008 to accommodate the Center’s continuing growth.
From the start, Monell’s science took a true multidisciplinary approach. Academic institutions traditionally are organized by disciplines into autonomous departments that often do not readily communicate with each other. For-profit research facilities tend to investigate specific areas of biochemical, molecular, or behavioral research in a somewhat autonomous fashion. In contrast, everything possible is done to ensure that Monell scientists – psychologists, biologists, chemists, neuroscientists, geneticists and others – can and will collaborate toward the common objective of understanding the chemical senses. The Center has no departmental structure; its laboratories and offices generally are not segregated by discipline, and most importantly its staff is imbued with the ideal of multidisciplinary interaction.
An integral part of Monell’s mission has always been preparation of the next generation of scientists through pre-doctoral and post-doctoral training programs. Since 1969, more than 400 PhD-level scientists have been trained at Monell. Most continue to contribute to the field through their work in academia, industry and government. The Center’s highly successful high school and college internship program introduces younger students to science and research through direct hands-on mentored experience in Monell’s labs.
LEADERSHIP
On October 1, 2014, Robert F. Margolskee, MD, PhD, became the Center’s third Director. A pioneer in the application of molecular biology to the study of taste, Margolskee succeeded Gary K. Beauchamp, PhD, who had served as Director for 24 years.
Many eminent scientists, academicians and business executives have served the Center as board members and members of advisory committees. Dwight Riskey, PhD, retired Senior Vice President, Consumer & Customer Insights at PepsiCo and current principal of Riskey Business Solutions, LLC, was elected Chair of Monell’s Board of Directors in October 2007. Monell also has benefited from the leadership of three distinguished individuals who previously served as Board Chairs: J. George Harrer (former president of the Ford Foundation), Lewis Thomas (emeritus chief executive officer of Memorial Sloan-Kettering Cancer Center and National Book Award recipient) and Martin Meyerson (emeritus president of the University of Pennsylvania).
SENSING THE FUTURE
Other institutions conduct outstanding basic and clinical research on taste and olfaction. However, no other institution or group of scientists has the history, depth and breadth of Monell’s multidisciplinary approach, nor can they integrate research findings into an overall vision of the field. Current fundamental studies promise to provide new insights and avenues for major progress in understanding taste and smell, just as early pioneering studies at Monell provided the basis for what is known today.
Over the past 50 years, the Monell Center has transformed the way science is done. Today, we are building on our legacy of fundamental discovery to lead the way to a healthier future for us all.
Notable Clients
University of Pennsylvania
Notable Accomplishments / Recognition
Monell’s collaborative philosophy pervades the Center’s laboratories and hallways and extends to the outside world: valuable partners from the realms of academia, government, and industry add depth and breadth to the Center’s research efforts.
Multidisciplinary Science at Monell
From the start, Monell’s science has been predicated on a true multidisciplinary approach. Monell researchers – psychologists, chemists, neuroscientists, biologists, geneticists and others – collaborate toward the common objective of a comprehensive understanding of taste and smell. Monell has no departmental structure; its laboratories and offices are not segregated by discipline, and most importantly, its staff is imbued with the ideal of multidisciplinary interaction.
Academia
Monell’s external collaborative network is extensive, bringing added strength and expertise to the Center’s research mission. Scientists from outside institutions who have particularly strong collaborative ties are appointed to become members of the Affiliate Faculty.
Since its inception, the Monell Center has been closely associated with the University of Pennsylvania. Originally established as an institute at Penn, Monell now operates as an independent nonprofit organization, but retains many ties with the University.
Members of Monell’s faculty hold adjunct appointments in departments and schools throughout Penn, including the Schools of Medicine (Dermatology, Neuroscience), Veterinary Medicine (Anatomy, Animal Biology, Biochemistry), and Dental Medicine (Anatomy and Cellular Biology), and the College of Arts and Sciences (Psychology).
Monell scientists are members of and provide leadership for several Penn institutes, including the Institute of Neurological Sciences, the Institute for Diabetes, Obesity and Metabolism, the Diabetes and Endocrinology Research Center, Institute for Translational Medicine and Therapeutics, and the Genome Frontiers Institute.
Penn’s Clinical and Translational Research Center (CTRC) is available to Monell researchers for clinical studies. A member of Monell’s faculty sits on Penn’s IRB, which oversees research protocols from both institutions.
Many Monell scientists engage in rich collaborations with Penn faculty, including projects with researchers in the departments of Dermatology; Otorhinolaryngology, Head and Neck Surgery; Occupational and Environmental Medicine; Psychiatry; Medicine; Cardiology; Obstetrics and Gynecology; Biostatistics and Epidemiology; Bioengineering; Chemical and Biomolecular Engineering; and Psychology.
Penn faculty members frequently present at Monell’s in-house seminar series, facilitating the formation of productive collaborations. Similarly, Monell researchers regularly attend and present at Penn seminars and colloquia, and also lecture to classes at the undergraduate and graduate levels.
Additional past and present research projects have involved collaborations with Children’s Hospital of Philadelphia and the Wistar Institute, and also with researchers and clinicians at other local institutions, including Thomas Jefferson University, Drexel University, Rutgers, Swarthmore College and the Nemours/Dupont Hospital for Children.
Institutional Affiliations
Monell continues to enlarge its circle of formal partnerships with academic institutions around the world. These key partnerships bring valuable breadth and depth to the Center’s research by expanding its intellectual and technological resources and extending its geographic range.
Current Affiliations:
Beijing Institutes of Life Science, Chinese Academy of Sciences
Department of Clinical Neuroscience, Karolinska Institutet
Department of Culinary Arts & Food Science, Drexel University
Jefferson University
Pavlov Institute of Physiology of the Russian Academy of Sciences
Singapore Institute for Clinical Sciences, Biomedical Sciences Institute
State Key Laboratory of Oral Diseases, Sichuan University
Université Côte d’Azur
Zhejiang Gongshang University Monell-Zhejiang Gongshang Joint Sensory Science Laboratory
Industry
Since its inception, Monell has been at the vanguard of successful academic-industry partnerships. Today, over 50 companies from around the world help support Monell’s basic research through the Center’s Corporate Sponsorship program. Interactions with the Center’s corporate sponsors provide Monell scientists with insights into real-world problems, and contribute a different perspective from that typically seen in purely academic institutions.
Government
Monell’s major source of funding comes from competitive government research grants, primarily through the National Institutes on Deafness and Other Communicative Disorders at the National Institutes of Health, which provides support for both research and training.
Among the other NIH institutes that currently fund Monell’s biomedical research are the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute on Alcohol Abuse and Alcoholism, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Many of Monell scientists serve NIH and the greater scientific community as members of NIH study sections and committees.
Additional federal support comes from the Veteran’s Administration and the Department of Defense; the Commonwealth of Pennsylvania also provides funding for targeted projects.
Monell has a long-standing cooperative agreement with the USDA’s National Wildlife Research Center. To date, almost 200 publications on bird and wildlife chemical senses have resulted from the Monell-USDA affiliation, disseminating information on the biology and behavior of many animal and avian species along with knowledge to aid in effective management of wildlife resources.
Foundations
Foundation support is essential for Monell’s research and training programs. The Center especially recognizes the key role of The Ambrose Monell Foundation, which provided start-up funding in the 1960s and continues to actively guide and support the Center’s mission.
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Training is a way of life at Monell. Students and scientists interested in chemosensory research find the Center to be an outstanding resource for learning. Graduate students, postdoctoral fellows, and visiting scientists — more than 400 since Monell’s inception — have come from more than 20 countries to work and learn at Monell.
VISITING SCIENTISTS
Senior-level investigators, many on sabbatical leave from academic positions, come to Monell to collaborate with the Center’s faculty, learn new skills, or both. In addition, the Center’s corporate partners often send senior and junior scientists to Monell for specialized training and collaborative research opportunities. In both cases, the length of stay can range from several weeks to a year or more, depending upon the visiting scientist’s needs and interests.
POSTDOCTORAL FELLOWS
Monell’s strong postdoctoral program attracts beginning scientists from a wide range of disciplines. Approximately 20 post-doctoral fellows, many of whom have no previous formal training in the chemical senses, are trained at the Center each year.
Monell’s interdisciplinary approach is a central aspect of the postdoctoral training program. For example, fellows may be assigned to a faculty member doing research in sensory transduction and also work with a secondary preceptor studying developmental biology, or a fellow studying the molecular genetics of taste might also participate in parallel studies on behavior.
GRADUATE STUDY
Talented doctoral candidates benefit greatly from the specialized research environment at Monell. Through cooperative arrangements, a student can complete course work at the degree-granting institutions and carry out thesis and dissertation research at Monell. The selection of graduate students from a range of scientific backgrounds complements Monell’s interdisciplinary approach to training and research.
UNDERGRADUATE EXPERIENCE
Monell helps to educate and train undergraduate students through grants from local foundations, work-study programs and cooperative arrangements with the University of Pennsylvania and other nearby colleges and universities. Undergraduates from local universities may conduct their Honors Theses under the direction of Monell scientists.
During the summer, college students apprentice or volunteer their services at Monell to gain laboratory experience in the chemical senses. They, along with the Center’s high school student apprentices, participate in weekly seminars of research findings in taste and smell, and also attend seminars on scientific ethics, communication skills, and career planning. Field trips to nearby medical centers and corporate research facilities give students the opportunity to observe and interact with scientific and medical professionals in other settings. Findings from students’ research projects frequently are published in scientific journals.
SECONDARY EDUCATION
Since its inception, Monell’s scientists have made a strong commitment to the training of local high school students. Through partnerships with several area high schools, students interested in a career in science work during school hours as research apprentices at Monell and receive course credit. Many conduct their high school science projects under the guidance of Monell scientists.
Monell’s Science Apprenticeship Program brings at least 20 students, including many minority students, to the Center each summer for full-time participation. At the heart of the program is an intensive 7-week internship that allows students to participate in structured research experiences, as well as in a number of enrichment activities. Among the program’s many goals are an increased appreciation of the chemical senses, a demystification of science, the development of critical thought, and hands-on experience with the scientific process. A follow-up evaluation process has shown that the vast majority of apprentices pursue degrees in science.
Members of Monell’s staff also participate in local and international science fairs, serve as consultants to publishers of scientific educational materials, and help teachers develop new areas of classroom study.
TEACHING
Monell’s scientists teach courses in the chemical senses to undergraduate, graduate, and professional students in several departments and schools of the University of Pennsylvania, the Thomas Jefferson University, and other local colleges and universities. Members of the Center’s staff also lecture and offer programs to industrial, professional, and community groups.
SEMINARS AND CONFERENCES
An annual seminar series for staff and members of the academic community features presentations by specialists in the chemical senses and related fields. Monell scientists regularly present their own research for review during in-house seminars. Sharing of interdisciplinary information is a keystone of the Center’s operation.
Monell also hosts conferences and workshops attended by scientists from throughout the world. These meetings frequently combine the perspectives of basic research, development, and translation.
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PUBLICATIONS
Monell’s ‘product’ is knowledge, disseminated through scholarly publications and presentations at academic conferences. To date, Monell’s scientists have produced 2,000 book chapters and peer-reviewed journal articles, which appear in a broad spectrum of high-impact and specialized research, biomedical and clinical journals.
2016
Adappa, N. D., Farquhar, D., Palmer, J. N., Kennedy, D. W., Doghramji, L., Morris, S. A. et al. (2016). TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Int Forum Allergy Rhinol, 6, 25-33.
Adappa, N. D., Workman, A. D., Hadjiliadis, D., Dorgan, D. J., Frame, D., Brools, S. et al. (2016). T2R38 genotype is correlated with sinonasal quality of life in homozygous ?F508 cystic fibrosis patients. Int Forum Allergy Rhinol, 6, 356-61.
Dibattista, M., Reisert, J. (2016). The odorant receptor-dependent role of olfactory marker protein in olfactory receptor neurons. The Journal of Neuroscience, 36, 2995-3006.
Douglas, J. E., Saunders, C. J., Reed, D. R., Cohen, N. A. (2016). A role for airway taste receptor modulation in the treatment of upper respiratory infections. Expert Rev Respir, 10, 157-170.
Gerbe, F., Sidot, E., Smyth, D. J., Ohmoto, M., Matsumoto, I., Dardalhon, V. et al. (2016). Intestinal epithelial tuft cells initiate type 2 mucosal immunity helminth parasites. Nature, 529, 226-230.
Jensen, K. B., Regenbogen, C., Ohse, M. C., Frasnelli, J., Freiherr, J., Lundström, J.N. (2016). Brain activations during pain: a neuroimaging meta-analysis of patients with pain and healthy controls. Pain, 157, 1279-86.
Joseph, P. V., Reed, D. R., Mennella, J. A. (2016). Individual differences among children in sucrose detection thresholds Relationship with age, gender and bitter taste genotype. Nursing Research, 65, 3-12.
Juran, S. A., Lundström, J. N., Geigant, M., Kumlien, E., Fredrikson, M., Åhs, F. et al. (2016). Unilateral resection of the anterior medial temporal lobe impairs odor identification and valence perception. Frontiers in Psychology, 6, 2015.
Kimball, B. A., Cohen, A. S., Gordon, A. R., Opiekun, M., Martin, T., Elkind, J. et al. (2016). Brain injuries alters volatile metabolome. Chemical Senses, doi: 10.1093/chemse/bjw014.
Kimball, B. A., Stelting, S. A., McAuliffe, T. W., Stahl, R. S., Garcia, R. A., Pitt, W. C. (2016). Development of artificial bait for brown tree snake suppression. Biological Invasions, 18, 359-369.
Kimball, B. A., Wilson, D. A., Wesson, D. W. (2016). Alterations of the volatile metabolome in mouse models of Alzheimer's disease. Scientific Reports, 1-8.
Meada, N., Ohmoto, M., Yamamoto, K., Kurokawa, A., Narukawa, M., Ishimaru, Y. et al. (2016). Expression of serotonin receptor genes in cranial ganglia. Neuroscience Letters, 617, 46-51.
Mennella, J. A., Reiter, A., Pryor, L. (2016). Vegetable and fruit acceptance during infancy: Impact of ontogeny, genetics, and early experiences. Advances in Nutrition, 7, 211S-219S.
Mennella, J., Trabulsi, J. R., Papas, M. (2016). Effects of cow milk versus extensive protein hydrolysate formulas on infant cognitive development. Amino Acids, 48, 697-705.
Nakahara, T. S., Cardozo, L. M., Ibara-Soria, X., Bard, A. D., Carvvalho, V. M. A., Trintinalia, G. Z. et al. (2016). Detection of pup odors by non-canonical adult vomeronasal neurons expressing an odorant receptor gene is influenced by sex and parenting status. BMC Biology, doi: 10.1186/s12915-016-0234-9.
Nigri, A., Ferraro, S., Bruzzone, M. G., Nava, S., D'Incerti, L., Bertolino, N. et al. (2016). Central olfactory processing in patients with disorders of consciousness. European Journal of Neurology, 23, 605-612.
Parma, V. de Marchena, A. B. (2016). Motor signatures in autism spectrum disorder: The importance of variability. Journal of Neurophysiology, 115, 1081-1084.
Prokop-Prigge, K. A., Greene, K., Varallo, L., Wysocki, C. J., Preti, G. (2016). The effect of ethnicity on human axillary odorant production. Journal of Chemical Ecology, 42, 33-39.
Regenbogen, C., Johansson, E., Andersson, P., Olsson, M. J., Lundström, J. N. (2016). Bayesian-based integration of multisensory naturalistic perithreshold stimuli. Neuropsychologia, 29, 123-30.
Vingtdeux, V., Chang, E. H., Frattini, S. A., Zhao, H., Chandakkr, P., Adrien, L. et al. (2016). CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice. Science Reports, doi: 10.1038/srep24250.
Wise, P. M., Nattress, L., Flammer, L. J., Beauchamp, G. K. (2016). Reduced dietary intake of simple sugars alters perceieved sweet taste intensity but not perceieved pleasantness. American Journal of Clinical Nutrition, 103, 50-60.
2015
Alonso-Alonso, M., Woods, S. C., Pelchat, M., Grigson, P. S., Stice, E., Farooqi, S. et al. (2015). Food reward system: current perspectives and future research needs. Nutrition Reviews, 73, 296-307.
Baird, J. P., Tordoff, M. G., McCaughey, S. A. (2015). Bursting by taste-responsive cells in the rodent brainstem. Journal of Neurophysiology, 113, 2434-2446.
Beauchamp, G. K., Jiang, P. (2015). Comparative biology of taste: Insights into mechanism and function. Flavour, 4, 9.
Bobowski, N. (2015). Shifting human salty taste preference: Potential opportunities and challenges in reducing dietary salt intake of Americans. Chemosensory Perception, 8, 112-116.
Bobowski, N., Mennella, J. A. (2015). Disruption in the relationship between blood pressure and salty taste thresholds among overweight and obese children. Journal of the Academy of Nutrtion and Dietetics, 115, 1272-1282.
Cellini, N., Parma, V. (2015). Commentary: Olfactory aversive conditioning during sleep reduces cigarette-smoking behavior. Frontiers in Psychology, 6, 586.
Challis, R. C., Tian, H., Wang, J., He, J., Jiang, J., Chen, X. et al. (2015). An olfactory cilia pattern in the mammalian nose ensures high sensitivity to odors. Current Biology, 25, 2503-2512.
Cornelis, M. C., Byrne, E. M., Esko, T., Nalls, M. A., Ganna, A., Paynter, N. et al. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, 20, 647-656.
Du, L., Zou, L., Wang, Q., Zhao, L., Huang, L., Wang, P. et al. (2015). A novel biomimetic olfactory cell-based biosensor with DNA-directed site-specific immobilization of cells on a microelectrode array. Sensors and Actuators B: Chemicals, 217, 186-192.
Feng, P., Jotaki, M., Kim, A., Chai, J., Simon, N., Zhou, M. et al. (2015). Regulation of taste responses by tumor necrosis factor. Brain, Behavior, and Immunity, 49, 32-42.
Filiou, R. P., Lepore, F., Bryant, B., Lundstrom, J. N., Frasnelli, J. (2015). Perception of trigeminal mixtures. Chemical Senses, 40, 61-69.
Forestell, C. A., Mennella, J. A. (2015). The ontogeny of taste perception and preference throughout childhood. In R.L.Doty (Ed.), Handbook of Olfaction and Gustation (3rd ed.), New York: Marcell Dekker.
Glendinning, J. I., Stano, S., Holter, M., Azenkot, T., Goldman, O., Margolskee, R. F. et al. (2015). Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice. American Journal of Physiology, 309, R552-R560.
Hu, L., Wang, Q., Qin, Z., Su, K., Huang, L., Hu, N. et al. (2015). Detection of 5-hydroxytryptamine (5-HT) in vitro using a hippocampal neuronal network-based biosensor with extracellular potential analysis of neurons. Biosensors and Bioelectronics, 66, 572-578.
Hwang, L. D., Zhu, G., Breslin, P. A., Reed, D. R., Martin, N. G., & Wright, M. J. (2015). A common genetic influence on human intensity ratings of sugars and high-potency sweeteners. Twin Research and Human Genetics, 18, 361-367.
Kauer, J., Pelchat, M. L., Rozin, P., Zickgraf, H. F. (2015). Adult picky eating: Phenomenology, taste sensitivity, and psychological correlates. Appetite, 90, 219-228.
Lei, W., Ravoinjohary, A., Li, X., Margolskee, R. F., Reed, D. R., Beauchamp, G. K. et al. (2015). Functional analysis of bitter taste receptors in domestic cats (Felis catus). PLoS ONE, 10, e0139670.
Lekander, M., Karshikoff, B., Johansson, E., Soop, A., Fransson, P., Lundström, J. N. et al. (2015). Intrinsic functional connectivity of insular cortex and symptoms of sickness during acute experimental inflammation. Brain, Behavior, and Immunity, 56, 34-41.
Lowe, G. (2015). Slice blotting. Methods in Molecular Biology, 1312, 87-92.
Mainland, J. D., Li Y.R, Zhou, T., Liu, W. L. L., Matsunami, H. (2015). Human olfactory receptor responses to odorants. Scientific Data, doi:10.1038/sdata.2015.2
Malach, E., Shaul, M. E., Peri, I., Huang, L., Spielman, A. I., Seger, R. et al. (2015). Membrane-permeable tastants amplify beta2-adrenergic receptor signalling and delay receptor desensitization via intracellular inhibition of GRK2's kinase activity. Biochimica et Biophysica Acta, 1850, 1375-1388.
Mennella, J. A. (2015). The flavor world of childhood. Frontiers in Integrated Neuroscience. DOI:10.3389/conf.fnint.2015.03.00007
Mennella, J. A. & Bobowski, N. K. (2015). The sweetness and bitterness of childhood: Insights from basic research on taste preferences. Physiology & Behavior, 152, 502-507.
Mennella, J. A., Reed, D. R., Mathew, P. S., Roberts, K. M., Mansfield, C. J. (2015). "A spoonful of sugar helps the medicine go down": Bitter masking by sucrose among children and adults. Chemical Senses, 40, 17-25.
Mennella, J. A., Roberts, K., Mathew, P. S., Reed, D. R. (in press). Medication use among children: Genetics and taste. Archives of Diseases of Childhood.
Murovets, V. O., Bachmanov, A. A., Zolotarev, V. A. (2015). Impaired glucose metabolism in mice lacking the Tas1r3 taste receptor gene. PLoS ONE, 10, e0130997.
Mutic, S., Parma, V., Brünner, Y. F., Freiherr, J. (2015). You smell dangerous: Communicating fight responses through human chemosignals of aggression. Chemical Senses, 41, 35-43.
Pak, V. M., Keenan, B. T., Jackson, N., Grandner, M. A., Maislin, G., Teff, K. et al. (2015). Adhesion molecule increases in sleep apnea: beneficial effect of positive airway pressure and moderation by obesity. International Journal of Obesity, 39, 472-479.
Parma, V., Ferraro, S., Miller, S. S., Åhs, F., Lundström, J. N. (2015). Enhancement of odor sensitivity following repeated odor and visual fear conditioning. Chemical Senses, 40, 497-506.
Prokop-Prigge, K. A., Mansfield, C. J., Parker, M. R., Thaler, E., Grice, E. A., Wysocki, C. J. et al. (2015). Ethnic/racial and genetic influences on cerumen odorant profiles. Journal of Chemical Ecology, 41, 67-74.
Puzantian, H., Teff, K., Townsend, R. R. (2015). Investigating the effect of glucose on aortic pulse wave velocity using pancreatic clamping methodology. Biological Research for Nursing, 17, 270-275.
Reed, D. R., Xia, M. B. (2015). Recent advances in fatty acid perception and genetics. Advances in Nutrition, 6, 353S-360S.
Rickels, M. R., Fuller, C., Dalton-Bakes, C., Markmann, E., Palanjian, M., Cullison, K. et al. (2015). Restoration of glucose counterregulation by islet transplantation in long-standing type 1 diabetes. Diabetes, 64, 1713-8.
Rowland, H. M., Parker, M. R., Jiang, P., Reed, D. R., Beauchamp, G. K. (2015). Comparative taste biology with special focus on birds and reptiles. In Handbook of Olfaction and Gustation (pp. 957-982). John Wiley & Sons Inc.
Seubert, J., Ohla, K., Yokomukai, Y., Kellermann, K., Lundström, J. N. (2015) Superadditive opercular activation to food flavor is mediated by enhanced temporal and limbic coupling. Human Brain Mapping, 36, 1662-1676.
Spector, A. C., LeRoux, C. W., Munger, S. D., Sclafani, A., & Mennella, J. A. (2015). Taste signaling: impact on food selection, intake, and health. Journal of Parenteral and Enteral Nutrition, pii: 0148607115617438. [Epub ahead of print].
Takai, S., Yasumatsu, K., Inoue, M., Iwata, S., Yoshida, R., Shigemura, N. et al. (2015). Glucagon-like peptide-1 is specifically involved in sweet taste transmission. FASEB Journal, 29, 2268-2280.
Teff, K. L., Rickels, K., Alshehabi, E., Rickels, M. R. (2015). Metabolic impairments precede changes in hunger and food intake following short-term administration of second-generation antipsychotics. Journal of Clinical Psychopharmacology, 35, 579-582.
Tordoff, M. G., Aleman, T. R., Ellis, H. T., Ohmoto, M., Matsumoto, I., Shestopalov, V. I. et al. (2015). Normal taste acceptance and preference of PANX1 knockout mice. Chemical Senses, 40, 453-459.
Ventura, A., Mennella, J. A., Inamdar, L. (2015). Consistency in infants' behavioral signaling of satiation during bottle-feeding. Pediatric Obesity, 10, 180-7.
Vetter, M. L., Wadden, T. A., Teff, K. L., Khan, Z. F., Carvajal, R., Ritter, S. et al. (2015). GLP-1 plays a limited role in improved glycemia shortly after Roux-en-Y gastric bypass: a comparison with intensive lifestyle modification. Diabetes, 64, 434-446.
Wahlqvist, M. L., Krawetz, S. A., Rizzo, N. S., Dominguez-Bello, M. G., Szymanski, L. M., Barkin, S. et al. (2015). Early-life influences on obesity: from preconception to adolescence. Annals of the New York Academy of Sciences, 1347, 1-28.
Yoshida, R., Noguchi, K., Shigemura, N., Jyotaki, M., Takahashi, I., Margolskee, R. F. et al. (2015). Leptin suppresses mouse taste cell responses to sweet compounds. Diabetes, 64, 3751-3762.
Zellner, D. A., Cobuzzi, J. L. (2015). Just dessert: Serving fruit as a separate ''dessert" course increases vegetable consumption in a school lunch. Food Quality and Preference, 48, 195-198.
2014
Bachmanov, A. A., Bosak, N. P., Lin, C., Matsumoto, I., Ohmoto, M., Reed, D. R. et al. (2014). Genetics of taste receptors. Current Pharmaceutical Design, 20, 2669-2683.
Baldéon, M. E., Mennella, J. A., Flores, N., Fornasini, M., Gabriel, A. S. (2014). Free amino acid content in breast milk of adolescent and adult mothers in Ecuador. SpringerPlus, 3, doi: doi:10.1186/2193-1801-3-104.
Boesveldt, S., Lundström, J. N. (2014). Detecting fat content of food from a distance: Olfactory-based fat discrimination in humans. PLoS ONE, 9, e85977.
Campbell, M. C., Ranciaro, A., Zinstheyn, D., Rawlings-Goss, R., Hirbo, J., Thompson, S. et al. (2014). Limited evidence for adaptive evolution and functional effect of allelic variation at rs702424 in the promoter of the TAS2R16 bitter taste receptor gene in Africa. Journal of Human Genetics, 59, 349-352.
Campbell, M. C., Ranciaro, A., Zinstheyn, D., Rawlings-Goss, R., Hirbo, J., Thompson, S. et al. (2014). Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. Molecular Biology and Evolution, 31, 288-302.
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2013
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2012
Adipietro, K.A.; Mainland, J.D.; Matsunami, H. (2012) Functional evolution of mammalian odorant receptors. PloS Genetics, 8, e1002821.
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Glendinning, J.I.; Gillman, J.; Zamer, H.; Margolskee, R.F.; Sclafani, A. (2012) The role of T1R3 and TRPM5 in carbohydrate-induced obesity in mice. Physiology & Behavior, 107, 50-58.
Golden, G.J.; Hussey, A.M.; Kimball, B.A. (2012) Do gastrointestinal taste receptors contribute to associative learning and foraging behavior? Journal of Animal Science, 90, 4297-4307.
Golden, G.J.; Voznesenskaya, A.; Tordoff, M. (2012) Chorda tympani nerve modulates the rat’s avoidance of calcium chloride. Physiology & Behavior, 105, 1214-1218.
Gyekis, J.P.; Dingman, M.A.; Revitsky, A.R.; Bryant, B.P.; et al. (2012) Gustatory, trigeminal, and olfactory aspects of nicotine intake in three mouse strains. Behavior Genetics, 42, 820-829.
Hanai, Y.; Shimono, K.; Oka, H.; Baba, Y.; Yamazaki, K.; Beauchamp, G.K. (2012) Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. Cancer Cell International, 12, 7.
Hanai, Y.; Shimono, K.; Matsumura, K.; Vachani, A.; Albedla, S.; Yamazaki, K.; Beachamp, G.K.; Oka, H. (2012) Urinary volatile compounds as biomarkers for lung cancer. Bioscience, Biotechnology, and Biochemistry, 76, 679-684.
Ishiwatari Y.; Bachmanov A.A. (2012) NaCl taste thresholds in 13 inbred mouse strains. Chemical Senses, 37, 497-508.
Jadauji, J.B.; Djordjevic, J.; Lundström, J.N.; Pack, C.C. (2012) Modulation of olfactory perception by visual cortex stimulation. Journal of Neuroscience, 32, 3095-3100.
Jiang, P.; Josue, J.; Li, X.; Glaser, D.; Li, W.; Brand, J.G.; Margolskee, R.F.; Reed, D.R.; Beauchamp, G.K. (2012) Major taste loss in carnivorous mammals. Proceedings of the National Academy of Sciences, USA, 109, 4956-4961.
Jiang, P.; Josue, J.; Li, X.; Glaser, D.; Li, W.; Brand, J.G.; Margolskee, R.F.; Reed, D.R.; Beauchamp, G.K. (2012) Reply to Zhao and Zhang: Loss of taste receptor function in mammals is directly related to feeding specializations. Proceedings of the National Academy of Science, USA, 109, e1465.
Khamis, S.M.; Jones, R.A.; Johnson, A.T.C.; Preti, G.; Kwak, J.; Gelperin, A. (2012) DNA-decorated carbon nanotube-based FETS as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers. AIP Advances, 2, 022110-1-11.
Kim, A.; Feng, P.; Ohkuri, T.; Sauers, D.; Cohn, Z.J.; Chai, J.; Nelson, T.; Bachmanov, A.A.; Huang, L.; Wang, H. (2012) Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune disease. PloS ONE, 7, e35588.
Knaapila, A.; Gu, Z.; Medland, S.; Wysocki, C.; Montgomery, G. W.; Martin, N.G.; Wright, M.J.; Reed, D.R. (2012) A genome-wide study on the perception of the odorants androstenone and galaxolide. Chemical Senses, 37, 541-552.
Knaapila, A.; Hwang, L.D.; Lysenko, A.; Duke, F.F.; Fesi, B.; Khoshnevisan, A.; James, R.S.; Wysocki, C.J.; Rhyu, M.; Tordoff, M.G.; Bachmanov, A.A.; Mura, E.; Naga,i H.; Reed, D.R. (2012) Genetic analysis of chemosensory traits in human twins. Chemical Senses, 37, 869-881.
Kwak, J. (2012) Challenges in quantitative analyses for volatile organic compounds bound to lipocalins. Journal of Separation Science, 35, 2929-2931.
Kwak, J.; Grigsby, C.; Rizki, M.; Preti, G.; Köksal, M.; Josue, J.; Kunio, Y.; Beauchamp, G.K. (2012) Differential binding between volatile ligands and major urinary proteins due to genetic variation in mice. Physiology & Behavior, 107, 112-120.
Lipchock, S.V.; Reed, D.R.; Mennella, J.A. (2012) Relationship between bitter-taste receptor genotype and solid mediation formulation usage among young children: a retrospective analysis. Clinical Therapeutics, 34, 728-733.
Lowe, G. (2012) Introduction to olfaction – physiology. In: Nakamoto, T. (Ed.) Human Olfactory Displays and Interfaces: Odor Sensing and Presentation. IGI Global. pp.1-43.
Lukasewycz, L.D.; Mennella, J.A. (2012) Lingual tactile acuity and food texture preference in children and their mothers. Food Quality and Preference, 26, 58-66.
Lunde, K.; Egelandsdal, B.; Skuterud, E.; Mainland, J.; Hersleth, M.; Matsunami, H. (2012) Genetic variation of an odorant receptor OR7D4 and sensory perception of cooked meat containing androstenone. PloS ONE, 7, e35259.
Lundström, J.N.; Gordon, A.R.; Wise, P.; Frasnelli, J. (2012) Individual differences in the chemical senses: is there a common sensitivity? Chemical Senses, 37, 371-378.
Mainland, J.; Matsunami, H. (2012) RAMP like proteins: RTP and REEP family of proteins. In: Spielman, W.S.; Parameswaran, N. (Eds.). RAMPS. pp. 75–86.
Maislin, G.; Ahmed, M.M.; Gooneratne, N; Thorne-Fitzgerald, M.; Kim, C.; Teff, K.L; et al. (2012) Single slice vs. volumetric MR assessment of visceral adipose tissue: Reliability and validity among the overweight and obese. Obesity, 20, 2124-2132.
Mandel, A.L.; Breslin, P.A. (2012) High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults. Journal of Nutrition, 142, 853-858.
Matsumoto, I.; Makoto, O. (2012) Taste receptor cell fate determined by Skn-1a. Chemistry & Biology, 50, 312-314.
McRae, J.F.; Mainland, J.D.; Jaeger, S.R.; Adipietro, K.A.; Matsunami, H.; Newcomb, R.D. (2012). Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the “grassy” smelling odor, cis-3-hexen-1-ol. Chemical Senses, 37, 585-593.
Mennella, J.A. (2012) Alcohol use during lactation: Effects on the mother-infant dyad. In: Watson, R.R.; Preedy, V. (Eds.). Nutrition and Alcohol: Linking Nutrient Interactions and Dietary Intake. CRC Press. pp. 63-82.
Mennella, J.A.; Castor, S.M. (2012) Sensitive period in flavor learning: effects of duration of exposure to formula flavors on food likes during infancy. Clinical Nutrition, 31, 1022-1025.
Mennella, J.A.; Finkbeiner, S.; Reed, D.R. (2012) The proof is in the pudding: children prefer lower fat but higher sugar than do mothers. International Journal of Obesity, 36, 1285-1291.
Mennella, J.A.; Trabulsi, J.C. (2012) Complementary foods and flavor experiences: setting the foundation. Annals of Nutrition and Metabolism, 60 S2, 40-50.
Miller, S.S.; Gordon, A.R.; Olsson, M.J.; Lundström, J.N.; Dalton, P. (2012) Mind over age: Social priming and olfactory function. Chemical Senses, 38, 167-174.
Mitro, S.; Gordon, A.R.; Olsson, M.J.; Lundström, J.N. (2012) The smell of age: perception and discrimination of body odors of different ages. PloS ONE, 7, e38110.
Nosrat, I.V.; Margolskee, R.F.; Nosrat, C.A. (2012) Targeted taste cell-specific overexpression of brain-derived neurotrophic factor in adult taste buds elevates phosphorylated trkb protein levels in taste cells, increases taste bud size, and promotes gustatory innervation. Journal of Biological Chemistry, 287, 16791-16800.
Ohla, K.; Busch, N.A.; Lundström, J.N. (2012) Time for taste – early cerebral processing of gustatory perception. Chemosensory Perception, 5, 87-99.
Olender, T.; Waszak, S.; Viavant, M.; Khen, M.; Ben-Asher, E.; Reyes, A.; Nativ, N.; Wysocki, C.; Ge, D.; Lancet, D. (2012) Personal receptor repertoires: Olfaction as a model. BMC Genomic, 13, 414.
Ozdener, M.H. (2012) Fishing for flavors: Where and how. Nature. (Electronic Citation) doi:10.1038/486S14a
Ozdener, M.H.; Rawson, N.E. (2012) Exogenous EGF and BDNF treatment triggered cultured taste cell differentiation and proliferation. Turkish Journal of Medical Sciences, 42, 1-14.
Ozdener, M.H.; Spielman, A.I.; Rawson, N.E. (2012) Isolation and culture of human fungiform taste papillae cells. Journal of Visualized Experiments, 63, e3730.
Pepino, M.Y.; Mennella, J.A. (2012) Habituation to the pleasure elicited by sweetness in lean and obese women. Appetite, 58, 800-805.
Peyrot des Gachons, C.P.; Mura, E.; Speziale, C.; Favreau, C.J.; Dubreuil, G.F.; Breslin, P.A.S (2012) Opponency of astringent and fat sensations. Current Biology, 22, R829-830.
Ponissery Saidu, S.; Dibattista, M.; Matthews, H.R.; Reisert, J. (2012) Odorant-induced responses recorded from olfactory receptor neurons using the suction pipette technique. Journal of Visualized Experiments, 62, e3862.
Rawson, N.E.; Gomez, G.; Cowart, B.J.; Kriete, A.; Pribitkin, E.; Restrepo, D. (2012) Age-associated loss of selectivity in human olfactory sensory neurons. Neurobiology of Aging, 33, 1913-1919.
Reisert, J.; Gelperin, A. (2012) When does more give less in the olfactory system? Physiology News, 86, 18-21.
Stein, L.J.; Cowart, B.J.; Beauchamp, G.K. (2012) The development of salty taste acceptance is related to dietary experience in human infants: a prospective study. American Journal of Clinical Nutrition, 95, 123-129.
Stephan, A.B.; Tobochnik, S.; Dibattista, M.; Wall, C.M.; Reisert, J.; Zhao, H. (2012) The Na+/Ca2+ exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response. Nature Neuroscience,15, 131-137.
Su, C.Y.; Menuz, K.; Reisert, J.; Carlson, J.R. (2012) Non-synaptic inhibition between grouped neurons in an olfactory circuit. Nature, 492, 66-71.
Tordoff, M.G.; Alarcón, L.K.; Valmeki, S.; Jiang, P. (2012) T1R3: A human calcium taste receptor. Scientific Reports 2, 496, 1-4.
Tordoff, M.G.; Aleman, T.R.; Murphy, M.C. (2012) No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice. Physiology & Behavior, 10, 338-345.
Tordoff, M.G.; Jaji, S.A.; Marks, J.M.; Ellis, H.T. (2012) Macronutrient choice of BTBR.NZW mice cogenic for a 21-gene region of chromosome 17. Physiology & Behavior, 106, 556-561.
Trabulsi, J.C.; Mennella, J.A. (2012) Diet, sensitive periods in flavor learning, and growth. International Journal of Psychiatry, 24, 219-230.
Ventura, A.K.; Beauchamp, G.K.; Mennella, J.A. (2012) Infant regulation of intake: the effect of free glutamate content in infant formulas. American Journal of Clinical Nutrition, 95, 875-881.
Ventura, A.K.; San Gabriel, A.; Hirota, M.; Mennella, J.A. (2012) Free amino acid content in infant formulas. Nutrition and Food Science, 42, 271-278.
Wise, P.M.; Breslin, P.A.S.; Dalton, P. (2012) Sweet taste and menthol increases cough reflex thresholds. Pulmonary Pharmacology and Therapeutics, 25, 236-241.
Wise, P.; Mennella, J.A.; Finkbeiner, S. (2012) Impaired cough sensitivity in children of smokers. Nicotine and Tobacco Research,15, 603-607.
Wise, P.M.; Wysocki, C.J.; Lundström, J.N. (2012) Stimulus selection for intranasal sensory isolation: eugenol is an irritant. Chemical Senses, 37, 509-514.
Xu, J.; Cao, J.; Iguchi, N.; Riethmacher, D.; Huang, L. (2012) Functional characterization of bitter taste receptors expressed in mammalian testis. Molecular Human Reproduction, 19, 17-28.
Yasumatsu, K.; Ogiwara, Y, Takai S.; Yoshida, R.; Iwatsuki, K.; Torii, K.; Margolskee, R.F.; Ninomiya, Y. (2012) Umami taste in mice uses multiple receptors and transduction pathways. Journal of Physiology, 590, 1155-1170.
Zhu, X.; Li, Z.; Jiang, D.; Zhao, J.; Huang, L.; Zhang, J.; Huang, X. (2012) Characterization and expressional analysis of Dleu7 during Xenopus tropicalis embryogenesis. Gene, 509, 77-84.
2011
Bachmanov, A.A.; Bosak, N.; Floriano, W. B.; Inoue, M.; Li, X.; Lin, C.; Murovets, V.; Reed, D.R.; Zolotarev, V.; Beauchamp, G.K. (2011) Genetics of sweet taste preferences. Flavour and Fragrance Journal, 26, 286-294.
Baker, J.F.; Morales, M.; Qatanani, M.; Cucchiara, A.; Nackos, E.; Lazar, M.A.; Teff, K.L.; von Feldt, J.M. (2011) Resistin levels in lupus and associations with disease-specific measures, insulin resistance, and coronary calcification. Journal of Rheumatology, 38, 2369-2375.
Batchelor, D.J; Al-Rammahi, M.; Moran, A.W.; Brand, J.G.; Li, X.; Haskins, M.; et al. (2011) Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habits. American Journal of Physiology, 300, R67-R75.
Beauchamp, G.K.; Mennella, J.A. (2011) Flavor perception in human infants: development and functional significance. Digestion, 83 S1, 1-6.
Boesveldt, S.; Lindau, S.T.; McClintock, M.K.; Hummel, T.; Lundström, J.N. (2011) Gustatory and olfactory dysfunction in older adults: a national probability study. Rhinology, 49, 324-330.
Cherukuri, C.; McCaughey, S.A.; Tordoff, M. (2011) Comparison of differences between PWD/phj and C57BL/6J mice in calcium solution preferences and chorda tympani nerve responses. Physiology & Behavior, 102, 496-502.
Cowart, B.J. (2011) Smell and taste in aging. Perfumer and Flavorist, i 34-36.
Cowart, B.J. (2011) Taste dysfunction: a practical guide for oral medicine. Oral Diseases, i 2-6.
Dalton, P.; Mennella, J.A.; Maute, C.; Castor, S.M.; Silva-Garcia, A.; Slotkin, J.; et al. (2011) Development of a test to evaluate olfactory function in a pediatric population. The Laryngoscope, 121, 1843-1850.
Enomoto, T.; Ohmoto, M.; Iwata, T.; Uno, A.; Saitou, M.; Yamaguchi, T.; Kominami, R.; Matsumoto, I.; Hirota, J. (2011) Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice. Journal of Neuroscience, 31, 10159-10173.
Fisher, J.O.; Mennella, J.A.; Hughes, A.O.; Liu, Y.; Mendoza, P. (2011) Offering ‘dip’ promotes intake of a moderately-liked vegetable among preschoolers with genetic sensitivity to bitterness. Journal of the American Dietetic Association, 112, 235-245.
Frasnelli, J.; Albrecht, J.; Bryant, B.; Lundström, J.N. (2011) Perception of specific trigeminal chemosensory receptor agonists. Journal of Neuroscience, 189, 377-383.
Frasnelli, J.; Lundström, J.N.; Boyle, J.A.; Katsarkas, E.; Jones-Gotman, M. (2011) The vomeronasal organ is not involved in the perception of endogenous odors. Human Brain Mapping, 32, 450-460.
Freiherr, J.; Boesveldt, S.; Gordon, A.R.; Alden, E.C.; Hernandez, M.; Lundström, J.N. (2011) The 40-item Monell extended sniffin’ sticks identification test (MONEX-40). Journal of Neuroscience Methods, 205, 10-16.
Ghatpande, A.; Reisert, J. (2011) Olfactory receptor neuron responses coding for rapid odor sampling. Journal of Physiology, 589, 2261-2273.
Golden, G.; Ishiwatar, Y.; Theodorides, M.; Bachmanov, A.A. (2011) Effect of chorda tympani nerve transection on salt taste perception in mice. Chemical Senses, 36, 811-819.
Goldsmith, B.R.; Mitala, J.J.; Josue, J.; Castro, A.; Lerner, M.B.; Bayburt, T.H.; Khamis, S.M.; Jones, R.A.; Brand, J.G.; Sligar, S.G.; Luetje, C.W.; Gelperin, A.; et al. (2011) Biomimetic chemical sensors using nanoelectronic read out of olfactory receptor proteins. ACS Nano, 5, 5408–5416.
Grandner, M.A.; Patel, N.P.; Gehrman, P.R.; Xie, D.; Sha, D.; Perlis, L.; Gehrman, P.R.; Xie, D.; Sha, D.; Pigeon, W.R.; Teff, K.; et al. (2011) Obesity, diabetes and exercise predict sleep-related complaints in the American population. Journal of Public Health, 19, 463-474.
Greene, T.A.; Alarcon, S.; Thomas, A.; Berdougo, E.; Doranz, B. J.; Breslin, P.A.S.; Rucker, J.B. (2011) Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PloS ONE, 6, e20123.
Horn, C.C.; Murat, C.; Rosazza, M.; Still, L. (2011) Effects of gastric distension and infusion of umami and bitter taste stimuli on vagal afferent activity. Brain Research, 14, 53-60.
Hussey, A.M.; Kimball, B.A.; Friedman, J.M. (2011) Assessment of tannin variation in tamarisk foliage across a latitudinal gradient. The Open Environmental & Biological Monitoring Journal, 4, 32-35.
Iguchi, M.; Ohkuri, T.; Slack, J.P.; Zhong, P.; Huang, L. (2011) Sarco/Endoplasmic reticulum Ca2+-ATPases (SERCA) contribute to GPCR-mediated taste perception. PloS ONE, 6, e23165.
Jaén, C.; Ozdener, M.H.; Reisert, J. (2011) Mechanisms of chloride uptake in frog olfactory receptor neurons. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 197, 339-349.
Kimball, B.A.; Pfund, F.; Gourley, M.; Giffin, D.L.; Russell, J.H. (2011) Silvicultural attempts to induce browse resistance in conifer seedlings. International Journal Forestry Research, 2011, 108529.
Kimball, B.A.; Russell, J.H.; Ott, P.K. (2011) Phytochemical variation within a single plant species influences foraging behavior of deer. Oikos, 121, 743-751.
Kwak, J.; Josue, J.; Faranda, A.; Curran-Opiekun, M.; Preti, G.; Osada, K.; Yamazaki, K.; Beauchamp, G.K. (2011) Butylated hydroxytoluene is a ligand of urinary proteins derived from female mice. Chemical Senses, 36, 443-452.
Kwak, J.; Preti, G. (2011) Volatile disease biomarkers in breath: A critique. Current Pharmaceutical Biotechnology, 12, 1067-1074.
Li, X.; Bachmanov, A.A.; Maehashi, K.; Li, W.; Lim, R.; Brand, J.; Beauchamp, G.K.; Reed, D.R.; et al. (2011) Sweet taste receptor gene variation and aspartame taste in primates and other species. Chemical Senses, 36, 453-475.
Lipchock, S.V.; Reed, D.R.; Mennella, J.A. (2011) The gustatory and olfactory systems during infancy: implications for development of feeding behaviors in the high-risk neonate. Clinics in Perinatology, 38, 627-641.
Liu, B.; Ha, M.; Meng, X.Y.; Kaur, T.; Khaleduzzaman, M.; Zhang, Z.; Jiang, P.; Li, X.; Cui, M. (2011) Molecular mechanism of species-dependent sweet taste toward artificial sweeteners. Journal of Neuroscience, 31, 11070-11076.
Lundström, J.N.; Boesveldt, S.; Albrecht, J. (2011) Central processing of the chemical senses: An overview. ACS Chemical Neuroscience, 2, 5-16.
Mandel, A.L.; Ozdener, M.H.; Vainius, A.A. (2011) Brain-derived neurotrophic factor in human saliva: ELISA optimization and biological correlates. Journal of Immunoassay and Immunochemistry, 32, 18-30.
Matsumoto, I. (2012) Neural pathway of tastes In: Touhara, K. (Ed.). Chemosensory Sciences. Kyoto: Kagaku Dojin.
Matsumoto, I.; Ohmoto, M.; Narukawa, M.; Yoshihara, Y.; Abe, K. (2011) Skn-1a/Pou2f3 specifies taste receptor cell lineage. Nature Neuroscience, 14, 685-687.
Mennella, J.A. (2011) Taste and smell. In: Swaiman, K.F.; Ashwall, S.; Ferriero, D. (Eds.) Pediatric Neurology: Principles and Practice; 5th edition. Philadelphia, PA: Saunders, e126.
Mennella, J.A.; Lukasewycz, L.D.; Castor, S.M.; Beauchamp, G.K. (2011) The timing and duration of a sensitive period in human flavor learning: a randomized trial. American Journal of Clinical Nutrition, 93, 1019-1024.
Mennella, J.A.; Lukasewycz, L.D.; Griffith, J.W.; Beauchamp, G.K. (2011) Evaluation of a forced-choice, paired-comparison tracking procedure method for determining taste preferences across the lifespan. Chemical Senses, 36, 345-355.
Mennella J.A.; Pepino, M.Y.; Duke, F.; Reed, D.R. (2011) Psychophysical dissection of genotype effects on human bitter perception TAS2R38. Chemical Senses, 36, 161-167.
Mennella, J.A.; Ventura, A.K. (2011) Early feeding: Setting the stage for healthy eating habits. Nestle Nutrition Workshop Series Pediatric Program, 68, 153-163.
Mennella, J.A.; Ventura, A.K.; Beauchamp, G.K. (2011) Differential growth patterns among healthy infants fed protein hydrolysate or cow-milk formulas. Pediatrics, 127, 110-118.
Mennella, J.A.; Ventura, A.K.; Lipchock, S.V. (2011) Le origini della preferenza del cibo (The origins of food preferences). In: Bellieni, C. (Ed.). Foetal Sensory Perception. Sienna, Italy: Edizioni Cantagalli Srl. pp. 33-50.
Ohmoto, M.; Okada, S.; Nakamura, S.; Abe, K.; Matsumoto, I. (2011) Mutually exclusive expression of G?ia and G?14 reveals diversification of taste receptor cells in zebrafish. Journal of Comparative Neurology, 519, 1616-1629.
Ozdener, M.H.; Rawson, N.E. (2011) Culture and maintenance of taste cells in vitro. In Vitro Cellular & Developmental Biology, 47, 513-514.
Ozdener, M.H.; Brand, J.G.; Speilman, F.G.; Lischka, F.W.; Teeter, J.; Breslin, P.A.S.; Rawson, N.E. (2011) Characterization of human fungiform papillae cells in culture. Chemical Senses, 36, 601-612.
Pelchat, M.L.; Bykowski, C.; Duke, F.F.; Reed, D.R. (2011) Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. Chemical Senses, 36, 9-17.
Peyrot des Gachons, C.; Beauchamp, G.K.; Stern, R.M.; Koch, K.L.; Breslin, P.A.S. (2011) Bitter taste induces nausea. Current Biology, 21, R247-R248.
Peyrot des Gachons, C.; Uchida, K.; Bryant, B.P.; Shima, A.; Sperry, J.B.; Dankulich-Nagrudny, L.; Smith, A.B., III; Beauchamp, G.K.; Breslin, P.A.S. (2011) Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal. Journal of Neuroscience, 31, 999-1009.
Rawson, N.E.; Gomez, G.; Cowart, B.J.; Kriete, A.; Pribitkin, E.A.; Restrepo, D. (2011) Age-associated loss of selectivity in human olfactory sensory neurons. Neurobiology of Aging, 33, 1913-1919.
Reed, D.R.; Duke, F.F.; Ellis, H.K.; Rosazza, M.R.; Lawler, M.P.; Alarcon, L.K.; Tordoff, M.G. (2011) Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats. Physiology & Behavior, 103, 523-529.
The Center’s most recent publications (2011-2016) can be viewed below.
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