Company Profile

Job DescriptionGeneral Summary:The Senior Director, Strategic and Portfolio Finance is a key leader within Vertex's Finance organization, responsible for driving strategic decision support across the enterprise portfolio and leading long-range financial planning processes. This role defines and delivers the vision for portfolio decision-making, integrating financial and non-financial metrics to enable informed trade-offs and strategic alignment. The position plays a critical role in ensuring ...

Job DescriptionGeneral Summary:The RWE Associate Director is an integral member of the RWE team who leverages expertise in epidemiology and real-world data to develop fit-for-purpose observational research and to inform internal and external stakeholders on the natural history (NH) of disease and real-world outcomes within their assigned therapeutic area. The RWE Associate Director works cross-functionally to support the execution of observational research across the portfolio. Key Duties ...

Job DescriptionThe Formulation Research Scientist will work with other scientists dedicated to advancing drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools to design and select dosage forms and manufacturing process. Key Duties and Responsibilities:Develop dosage forms for clinical and commercial use Develop stable and bioavailable formulations for different stages of development (e.g., ...

Job DescriptionKickstart Your Career at Vertex!Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, ...

Job DescriptionAs a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing Enterprise Third-party Risk Process & Governance leader is responsible for leading the operational execution of the end-to-end third party risk process as a key member of the Central Risk Management team. This role is responsible for shaping, driving and managing central third-party risk management processes, supporting cross-functional teams, and ensuring consistent application ...

Job DescriptionThe Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations (BSMO) is a key member of Vertex's Financial Planning & Analysis team. This role will partner closely with Commercial Manufacturing and Tech Ops (CMTO), Commercial Finance and Disease Strategy Team (DST) Finance in support of our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-ever approved CRISPR-based gene-editing therapy used to treat Sickle ...

Job DescriptionGeneral Summary:The Clinical Trial Management Principal is responsible for leading global or regional-based activities on complex clinical trials across a range of study phases (Phases 1 through 4, including Real World Evidence trials) and therapeutic areas. In the global role, the Clinical Trial Management Principal leads the global cross-functional Study Team, ensuring that deliverables are met, quality is maintained throughout the lifecycle of the trial, and the study budget ...

Job DescriptionGeneral Summary Vertex is seeking a hands-on, strategic, and collaborative Director of Talent Acquisition to lead talent acquisition efforts across all U.S. Commercial Business Units. The ideal candidate is a bold, business-minded talent advisor who thrives in a fast-paced, matrixed environment and is passionate about building teams that drive commercial excellence. The Director will serve as a trusted partner to senior leaders, shaping and executing talent strategies that align ...

Job DescriptionGeneral Summary:The Medical Affairs Associate Medical Director will provide medical leadership for the Medical Department in the Pain therapeutic area. This role will be accountable for working with the medical team for North America, for the development and implementation of the North American Medical strategy and plans and will work in partnership with cross functional team colleagues to ensure access to company's products, develop and implement cross functional country plans ...

Job DescriptionGeneral Summary:The Senior Director, Regulatory Strategy, Rest of World (ROW) is responsible for regulatory strategy and execution of submissions in the ROW region, including the planning and coordinating of complex regulatory submissions, e.g., MAAs and new therapeutic indications, and will also represent RA on multidisciplinary teams. ROW is defined as the Vertex International region outside of Europe (EU, UK and CH, emerging markets & distributor markets). Key Duties and ...